Monkey Skin cDNA: A Powerful Tool for Gene Expression and Skin Biology Research
Monkey Skin cDNA is a high-quality complementary DNA derived from monkey (Macaca spp.) skin tissue, widely used in molecular biology, biomedical research, and functional genomics. This tissue-specific cDNA provides an accurate representation of gene expression in primate skin, offering a valuable model for human skin-related studies.
🔍 What Is Monkey Skin cDNA?
Monkey Skin cDNA is synthesized from mRNA extracted from monkey skin tissue, then reverse transcribed into DNA. It captures the actively expressed genes in skin cells, making it ideal for:
- Gene expression analysis
- PCR and qPCR validation
- Transcriptome profiling
- Comparative genomics
- Skin disease modeling
By using tissue-specific cDNA, researchers can focus on genes that are biologically relevant to skin function, structure, and development.
🧪 Key Benefits of Monkey Skin cDNA
| Feature | Benefit |
|---|---|
| Species-specific | Derived from cynomolgus or rhesus monkey (Macaca spp.)—closely related to humans |
| Tissue-targeted | Reflects active skin-specific genes |
| High Quality | Validated for purity and integrity for PCR, qPCR, RNA-seq |
| Ready-to-use | Save time and reduce error in sample preparation |
| Reproducible | Consistent results across experiments and batches |
🧬 Applications in Molecular and Biomedical Research
- Gene Expression Profiling: Discover skin-specific or disease-associated genes.
- Comparative Transcriptomics: Compare monkey and human skin gene expression.
- RT-PCR & qPCR Validation: Use as a template for gene amplification studies.
- Cloning and Isoform Discovery: Clone full-length genes or study alternative splicing.
- Functional Genomics: Analyze gene function in vitro using expression vectors.
🧠 Why Use Monkey cDNA in Skin Research?
Monkey models (especially Macaca fascicularis and Macaca mulatta) are genetically similar to humans and are widely used in dermatology, pharmacology, and cosmetic science. Skin-derived cDNA allows researchers to:
- Study collagen, keratin, and melanin-related genes
- Explore UV sensitivity, barrier function, and wound healing pathways
- Validate targets for anti-aging or anti-inflammatory treatments
🔬 Real Scientific Study Example
A study published in Genome Biology and Evolution used RNA-Seq of skin tissue from primates to identify 31 differentially expressed genes, many of which were related to structural proteins like COL18A1, BGN, and LAMB2 all upregulated in humans compared to monkeys (PMC6402313).
This highlights the value of monkey skin cDNA in evolutionary biology and regulatory gene expression research.
🛒 Where to Buy Monkey Skin cDNA
Several biotechnology companie offer validated monkey skin cDNA:
